Wade Wilson is Deadpool, the Merc with a Mouth and a healing factor that just won't quit! Nathan Summers is Cable, the mutant from the future who plans to save us all - whether we want him to or not! And now this disparate duo has just become Marvel's oddest couple - because they're stuck with one another! Can two grown men armed to the teeth with high-tech weaponry coexist without driving each other crazy?! It's action, adventure, time travel, dimension-hopping, black humor, black ops, Bea Arthur, chimichangas - yes, that whole thing started here - and lots of gunfire as two of Marvel's fan-favorite antiheroes take on each other and everyone else! Guest-starring the X-Men, Spider-Man, Captain America, the Fantastic Four...and the Great Lakes Avengers! Collecting CABLE & DEADPOOL #1-50, DEADPOOL/GLA SUMMER FUN SPECTACULAR and material from DEADPOOL (2012) #27.